IVF with egg donation and sperm donation

IVF with egg donation and sperm donation


Definition: IVF with egg donation and sperm donation is a laboratory technique that consists of fertilizing a donor's eggs with the sperm of a donor, both anonymous




When is IVF with egg donation and sperm donation recommended?


The IVF with donor eggs and sperm is a laboratory technique of fertilizing donor eggs with the sperm of a donor, both anonymous. Once fertilized, the egg turns into a pre-embryo and is transferred to the uterus, previously prepared, so that it continues to grow there.

This technique is used when the patient has ovarian problems, due to age or unknown causes, and uses sperm donation because she wants to have a child alone because her partner is a woman or Because her male partner has problems with azoospermia (lack of spermatozoa) or other sperm diseases.

Phases of IVF with egg donation and sperm donation


1. Selection of the donor


The donors are selected by very strict medical criteria and are subjected to a series of complementary examinations to avoid any major pathology likely to have an impact on the health of the newborn.

One of the differential factors of our program is that the physical characteristics (Phenotype) of the donor and the recipient are as close as possible. This is to guarantee what doctors call a good "phenotypic complementarity." These findings are controlled by a physician who also ensures the absence of genetic diseases known to date in personal or family history, while a psychologist assesses the donor's mental health.

Finally, by Spanish law, the donor signs a consent by which she agrees to give her eggs to a couple wishing to have a child, and undertakes never to try to know their identity.


2. Treatment of the donor


The donor must undergo one or two weeks of ovarian stimulation therapy, which consists of subcutaneous injections of hormones, followed by ultrasound and blood Takes place. The ovules are extracted by ovarian puncture performed under sedation.


3. Doctors select the spermatozoa and prepare the sample


The sperm sample is taken from a donor who has undergone a complete medical examination (sperm analysis, blood and urine tests, general exploration, sexually transmitted diseases and psychological examination) to ensure the quality of his Spermatozoa and rule out any pathology. All donors are mature, sign a consent and commit to keeping their donation secret. The sperm is frozen before use.


4. Egg mining and in vitro fertilization


Extraction of the eggs is performed by aspiration and aspiration of the follicles. Once extracted, it is plunged a few hours into a culture medium, while semen is prepared to isolate the moving spermatozoa.

If the technique chosen is ICSI (microinjection of a spermatozoon in each ovule at maturity), the eggs are "bared," i.e., the cell ring surrounding them is removed and then injected A sperm in each of them. In our center, and without contraindication, Doctors practice the ICSI in 99% of the cases.

If this is not the case, the spermatozoa (50 to 100 000) are immersed in the culture medium where the ova are. The next day, Doctors verify how many of these have been fertilized. Obviously, the more eggs, the greater the chances of obtaining embryos.


5. Transfer


The day after the extraction and ICSI of the ova, it is known how many of them have been fertilized. The next two to three days, these fertilized eggs turn into pre-embryos ready to be transferred into the uterus.

On the day of the transfer, the pre-embryos which have the best development characteristics are selected. The law allows us to transfer up to 3 embryos, but the most usual average number is 2.

The pre-embryos, introduced into a very fine catheter, are led by the gynecologist to the bottom of the uterus. Anesthesia is not necessary. On the transferred pre-embryos, usually only one implant is implanted; It must be known that it may happen that many do so, giving rise to multiple pregnancies.

6. Cryopreservation


The pre-embryos which have not been transferred are frozen in liquid nitrogen (this cryopreservation is known as vitrification), after which, suitably labeled, they are stored in the embryo library. They can be used in subsequent cycles if the first attempt is not successful. Obviously, the preparation of the uterus for a transfer of frozen embryos is much simpler since the stimulation, and the extraction of eggs are not necessary

Success rate of IVF with egg donation and sperm donation


This is the complete information about IVF with egg donation and sperm donation. If you have any doubt please leave a comment.


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