IVF with egg donation and sperm from your partner

IVF with egg donation and sperm from your partner

DEFINITION: IVF with egg donation and sperm from your partner is a laboratory technique that involves fertilizing a donor's ova with your partner's sperm.

When is IVF with egg donation and sperm from your partner recommended?

The IVF with donor eggs and partner's sperm is a laboratory technique of fertilizing donor eggs with sperm from your partner. Once fertilized, the egg turns into a pre-embryo and is transferred to the uterus, previously prepared, so that it continues to grow there.

Spanish legislation establishes that the donation of eggs is anonymous (the recipient and the donor must not know each other at the time of donation or after) and voluntary (the sale of ova and embryos is illegal in Spain. Donors must be between 18 and 35 years of age and receive financial compensation for the time and energy spent on the donation.

This type of in vitro fertilization is recommended for ovarian problems requiring the use of donor eggs. It may happen that the ovaries do not produce eggs or that the eggs do not have the desired quality (see causes of female sterility ). This technique is also used when the patient has a genetic disorder, a chromosomal abnormality or a pathology with which ovarian stimulation is contraindicated.

It is also recommended after several unsuccessful attempts at assisted fertilization with its ovules, or if the patient is more than 43 years old, because at this age the fertility rate drops significantly and, even in the case of pregnancy, The risk of miscarriage and chromosomal abnormalities of the fetus increases.

Phases of IVF with egg donation and sperm from your partner

1. Selection of the donor

The donors are selected by very strict medical criteria and are subjected to a series of complementary examinations to avoid any major pathology likely to have an impact on the health of the newborn.

One of the differential factors of our program is that the physical characteristics (Phenotype) of the donor and the Receiver are as close as possible. This is to guarantee what we call a good "phenotypic complementarity." These findings are controlled by a physician who also ensures the absence of genetic diseases known to date in personal or family history, while a psychologist assesses the donor's mental health.

Finally, by Spanish law, the donor signs a consent by which she agrees to give her eggs to a couple wishing to have a child, and undertakes never to try to know their identity.

2. Treatment of the donor

The donor must undergo one or two weeks of ovarian stimulation therapy, which consists of subcutaneous injections of hormones, followed by ultrasound and blood Takes place. The ovules are extracted by ovarian puncture performed under sedation.

3. In vitro fertilization and embryo transfer

As with intra-conjugal in vitro fertilization (with ova and semen of the couple) after extraction, the donor's eggs are immersed for a few hours in a culture medium, while sperm is prepared to isolate the spermatozoa.

If the technique chosen is ICSI (microinjection of a spermatozoon in each egg at maturity), the eggs are "stripped." That is to say that the ring of cells surrounding them is removed and then injected A sperm in each of them. In our center, and without contraindication, we practice the ICSI in 99% of the cases.

With the classic IVF, the spermatozoa (50 to 100 000) are immersed in the culture medium where the ova are. The next day, we verify how many of these have been fertilized. Obviously, the more eggs and the better the quality of the sperm, the greater the chances of obtaining embryos. However, this technique has a disadvantage: fertilization rates are lower because the spermatozoa are not introduced directly into the ovum.

The day after the extraction and ICSI of the ova, it is known how many of them have been fertilized. The next two to three days, these fertilized eggs turn into pre-embryos ready to be transferred into the uterus. On the day of the transfer, the pre-embryos which have the best development characteristics are selected. The law authorizes us to transfer up to 3 embryos, but the most usual average number is 2. The pre-embryos, introduced into a very fine catheter, are led by the gynecologist to the bottom of the uterus. Anesthesia is not necessary. On the transferred pre-embryos, usually only one implant is implanted; It must be known that it may happen that many do so, giving rise to multiple pregnancies.

4. Cryopreservation

The pre-embryos which have not been transferred are frozen in liquid nitrogen (this cryopreservation is known as vitrification), after which, suitably labeled, they are stored in the embryo library. They can be used in subsequent cycles if the first attempt is not successful. Obviously, the preparation of the uterus for a transfer of frozen embryos is much simpler since the stimulation, and the extraction of eggs are not necessary.

Success rate of IVF with egg donation and sperm from your partner

This is the complete information about IVF with egg donation and sperm from your partner. If you have any doubt please leave a comment.

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